Reduced left ventricular compliance in human mitral stenosis. Role of reversible internal constraint.

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Reduced left ventricular compliance in human mitral stenosis. Role of reversible internal constraint.

BACKGROUND The mechanisms of depressed left ventricular (LV) pump performance in human mitral stenosis (MS) remain poorly understood, because reduced filling alone affects many hemodynamic measurements. Therefore, pressure-volume relations were examined in nine subjects with MS and compared with eight age-matched normal controls. METHODS AND RESULTS Data were obtained by conductance catheter/...

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Haemodynamic factors contributing to clinical disability in patients with rheumatic mitral stenosis have been under discussion and investigation for decades. Prior to the development of left heart catheterization, a low cardiac output in the presence of little or no pulmonary hypertension was taken as evidence for a myocardial 'insufficiency'. With the use of left heart catheterization, it was ...

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ژورنال

عنوان ژورنال: Circulation

سال: 1992

ISSN: 0009-7322,1524-4539

DOI: 10.1161/01.cir.85.4.1447